<p>4:21<i> Greet every saint in Christ Jesus. The brothers that are with me greet you</i>- &quot;Every saint&quot; is a reminder again that Paul is not writing just to the eldership. Every believer, including the illiterate and the slaves who could rarely attend meetings, were saints in Christ. Likewise in :22, &quot;All the saints...&quot;. Paul saw himself as facilitating person to person communication, real fellowship between ordinary people, and not just high level communication between elders. The brothers with Paul could refer to his fellow prisoners whom he had converted, or the few faithful friends who had come to Rome to minister to him. We note he does not extend greetings from the Roman church, with whom he seems to have parted company; for nobody stood with him at his final trial (2 Tim. 4:16). To die in such isolation from local brethren was a hard thing, but he clearly felt the Lord's personal presence with him compensating for it (2 Tim. 4:17).</p>